Study for first time shows lifelong exercise decreases cellular aging in the brain,
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In the first study to show that lifelong exercise decreases cellular aging in the brain,
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The research was presented today (Nov. McKnight chair for brain research in memory loss at the College of Medicine. "For this study animals were not forced to run; they did it because it was entertaining, the same as a pet hamster on a running wheel. The results show that regular mild exercise can prevent oxidative damage. In people,
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Oxidative damage in the brain is believed to be a natural consequence of aging and a contributor to memory loss. In addition,
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Oxidative damage can occur when molecules of oxygen gain electrons and become free radicals. The free radicals regain their balance by giving electrons to their neighbors. Most of the time the body routinely handles these renegades,
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At the end of the experiment, scientists examined chemical compounds in 41 tissue samples taken from a part of the brain important for balance and movement.

The more active rats were found to have fewer byproducts of oxidative stress in their brains. Fats known as lipids that help stabilize cell membranes,
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"The DNA for these animals after two years looked as if it were from their younger counterparts of only about 6 months of age,
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"The difference between humans and rats is that it isn’t as easy to get humans to exercise,
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The next step in the research is to determine which natural chemicals and mechanisms are triggered by exercise to fight oxidative stress,
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"By age 50 almost everyone has mild memory deficits," Foster said. "We forget where we put the keys or jumble the names of our kids. If these losses increase,
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