What screening tests are available?There are a variety of approaches to screening. Some tests are carried out in the first trimester and some in the second. They may include blood tests,
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Different tests have different detection rates,
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First trimester screeningFirst trimester screening includes a blood test that measures the levels of two proteins in your blood and a special ultrasound scan called a nuchal translucency (NT) test,
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The first trimester blood test measures two proteins that are produced by your placenta: free Beta hCG and PAPP A,
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The NT test measures the clear (translucent) space in the tissue at the back of your baby’s neck. Babies with chromosomal abnormalities tend to accumulate more fluid at the back of their neck during the first trimester,
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The NT screening can only be done between 11 weeks of pregnancy through the end of 13 weeks. (Because this test requires special training and equipment,
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Together,
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The advantage of first trimester screening is that you learn about your baby’s risk for chromosomal problems relatively early in the pregnancy. If the risk is low,
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If the risk is high,
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Second trimester screeningSecond trimester screening involves a blood test,
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The test measures the levels of four substances in your blood: AFP,
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Second trimester screening is generally offered in conjunction with first trimester screening as part of what’s known as integrated or sequential screening (see below),
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Integrated and sequential screeningIntegrated and sequential screening involve both first and second trimester screening tests,
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Integrated screening looks at the results of the first trimester blood test,
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Integrated screening detects 90 to 96 percent of Down syndrome cases. If the NT scan is not available,
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Integrated screening is the most accurate screening method currently available. Unfortunately,
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Your caregiver may offer you an alternate strategy,
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If the first trimester test result is negative (meaning the likelihood of a problem is low),
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What about the cell free fetal DNA blood test?Some providers are now offering a blood test that can detect Down syndrome and some other chromosomal conditions at 10 weeks of pregnancy or later. At this point,
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Second trimester screening can detect trisomy 18,
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This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child,
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